GlaxoSmithKline’s Technology Investment Board

Goal: To establish and implement a strategic approach to investments in step-change Drug Discovery and Development technologies.

Result:

1. •Identified short-term and long-term technology gaps across R&D.
   

2. •Identified business opportunities aligned with corporate gaps.
   

3. •Performed due diligence on business plans, potential ROI, technology development roadmaps, and intellectual property estates.
   

4. •Highlighted key challenges associated with technology and scientific validation.
   

5. •Defined strategic partnership approaches.
   

6. •Ensured that investment capital is allocated in a disciplined way.
   

7. •Monitored and supervised portfolio companies.
   

The Bill and Melinda Gates Foundation

Goal: To improve TB disease management by monitoring TB drug resistance around the world, and identifying new TB drug resistant strains.

Result:

1. Designed a core laboratory to monitor TB drug resistance and to focus specifically on surveillance. This laboratory has the capability to perform several genetic analysis protocols on patient samples to accurately and cost-effectively catalog the number and distribution of mutations associated with drug resistance and to help identify new genetic strains. The core lab design enabled the use of automated instrumentation and associated software to perform the following tasks:
   

2. •Collect Acid Fast Bacillus-stained sputum microscope slide smears (AFB smears)
   

3. •Extract and preserve biological material from AFB smears
   

4. •Store and retrieve the biological samples
   

5. •Genetically analyze samples
   

6. •Analyze, report, and track the data
   

Several Angel and Venture Capital Investors

Goal: To perform due diligence on investment candidates.

Result:

1. •Provided feedback on business plans.
   

2. •Assessed the immediate and long-term value of various start-up companies’ core capabilities to the biotechnology and pharmaceutical industries.
   

3. •Identified early adopters and recommended strategic partnership approaches.
   

4. •Evaluated and summarized the quality candidate’s science, technology development and business plans. Highlighted additional challenges the candidate should address.
   

5. •Evaluated candidate exit strategies and highlighted challenges to business models and financial projections.
   

A Life Sciences Government Funding Agency

Goal: To evaluate and prioritize funding proposals

Result:

1. •Provided expert feedback on numerous research proposals.
   

2. •Elaborated strategic research themes for funding in the Genomics and Proteomics fields.
   

3. •Participated on international review panel to prioritize funding opportunities and recommend investments.

Clients